Excellent binder
The material is excellent for bonding other granular augmentation materials, allowing easy handling and preventing particle migration thus obtaining predictable outcomes.

Versatile
In most cases BondBone™ does not require membrane coverage, when used as a composite graft for different kinds of defects or by itself. When used alone, it is ideal for obtaining a complete regeneration in defects that are less than 10 mm with at least three-wall bony support. It also can be used as a membrane over other augmenttion materials.

Easy handling
BondBone™ allows significant reduction in procedure time. The intitial pliable paste hardens in two to five minutes, allowing excellent handling time.

Adaptivity
Its setting isn not affected by the presence of blood or saliva.

Pure and safe
No human or animal orgin. BondBone™ does not contain any components other than cacium sulfate.

Osteoconductive
Its unique porus structure allows infiltration of growth factors through its micropores and angiogenesis, as well as cell proliferation through its macropores.

Completely resorbs
It is completely resorbed, leaving behind natural bone.

Effective bone regeneration, safety, and biocompatibility that have been clinically and scientifically proven for over 20 years in all areas of surgery.
4BONE is a fully synthetic bone substitute made of synthesized HA & ßTCP (60% / 40% ratio) an interconnected micro, and 70% macroporosity promotes the invasion of osteogenic cells by osteoconduction and allows biological fluid diffusion. The 4BONE contains optimized morphology and resorption properties that achieve predicable treatment outcomes. The unique packaging (syringe) has excellent wetting properties that allows a simple approach to handling the product. The 4BONE offers the practitioner flexibility in a large range of oral regeneration procedures.

Background
100% bone substitution, boasts the greatest clinical and fundamental literature review of 20 years of human and animal use of micro and macroporous biphasic calcium phosphate materials (4BONE.)

Safety
100% Synthetic. No human or animal orgin, 20 years of clinical studies have demonstrated efficiency, biocompatibility and safety of 4BONE bioceramic.

Efficiency
Bioactive, 4BONE allows cell attachment, proliferation and cell invasion.

Architectural Bone Remodeling
Specific microstructure and macrostructure represent a dynamic process, including physico-chemical processes, crystal/protein interactions, cell and tissue colonization and bone remodelling.

Easy
Easy to handle. The granules of the 4BONE bone replacement substance easily absorb the patient’s blood or physiological solution in the syringe, which is then used to easily apply the substance to the implant site.

Packing & Indications
The unique packing of 4BONE in a syringe, offers the clinician an easy procedure of mixing the substance with the patient’s blood and/r saline water. After the blood and/or saline water is fully absorbed in the 4BONE, placing the substance in the patient’s mouth is simple to perform with the syringe.

MIS 4BONE is indicated for filling and/or augmenting intra oral/maxillofacial osseous defects. The indications for using MIS 4BONE include bony hehiscenses and fenestrations around dental implants. 4BONE is also very efficient in immediate implanting.

Bone resorption/substitution
Facilitates architectural bone formation by providing an osteoconductive scaffolding, with a homogenous phase distribution that controls excessive resorption. 4BONE serves as a scaffold for one deposition during the bone formation process. The mechanical stability of the augmentated volume is maintained as a result of the slow resorption rate of hydroxapatite which prevents excessive resorption, unlike other biphasic calcium phosphates, 4BONE is not only a mixture of HA and TCP, but is chemically synthesized as a composite, in order to ensure homogeneous distribution of the two phases.

4BONE is integrated during the natural remodelling process for the human bone, and is replaced by natural bony crystals similar to human bone.

Effective bone regeneration, safety, and biocompatibility that have been clinically and scientifically proven for over 20 years in all areas of surgery.

4BONE benefits from the largest scientific and clinical literature on the market since 1986 (500 publications.)

4BONE SBS is used for new therapeutic processes based on tissue engineering procedures (bone reconstruction in irradiated sites.)

54Bone RCM is a resorbable porcine skin-sourced collagen type three dental membrane,that is used in guided tissue regeneration(GTR)and guided bone regeneration(GBR.It is manufactured using unique cross linkage technology that provides the mambrane with its ability to stay intact 4-6 months 4bone RCM is indicated for use in oral surgery procedures to assist in wound healing.